The 5S approach is one of the strategies that can assist organizations, corporations, and educational institutions boost production and working efficiency. The Training Department - Thu Dau Mot University has used and implemented this strategy to create a clean and tidy working environment in which personnel can handle professional work and systematic archival records. This article presents the theoretical basis of the 5S method, the application process, and the results of implementing this method in the management of training at Thu Dau Mot University. Based on the approach to 5S principles, implementation steps according to the PDCD quality cycle, and practical implementation at the Training Department. The outcomes benefited the department by increasing work management efficiency without spending too much money. If 5S is adopted and reproduced in all functional departments and specialized units, it will generate a high-quality cultural environment that will strengthen the university's market position.