Binh Duong Province is one of the leading regions in Vietnam in attracting foreign investment, with thousands of expatriates living and working in the province. The demand for an international education environment (in-country study abroad) among parents and students in the province is increasing. Additionally, the current globalization trend and international integration demand a high-quality workforce with adaptability and international integration skills, requiring educational institutions to innovate to keep up with the rapidly changing society. Given the situation and trends, establishing an international high school under Thu Dau Mot University (TDMU) is necessary to meet the demand for high-quality human resources in Binh Duong Province, serving the economic, social development, and international integration of the province, the Southeast region, and the whole country. Furthermore, the establishment of an international high school by TDMU also contributes to enhancing TDMU’s position, image, and reputation within the national and international education systems. This article analyzes the strengths, weaknesses, challenges, and opportunities of TDMU in establishing an international high school, thereby providing implementation directions in the context of the economic and social situation in Binh Duong Province.